Spider-Man Collectible Series #16

In "The Terrible Threat of the Living Brain!", Peter Parker faces a bizarre new menace when a stolen school display computer awakens as a sentient, rampaging entity. With Flash Thompson joining the fray, the two clash in a high-stakes showdown inside the school’s boxing ring—just as the Living Brain begins to wreak havoc. Written by Stan Lee and illustrated by Steve Ditko, with colors by Stan Goldberg and letters by Art Simek, this 2006 issue features a cover by Ron Frenz and Al Milgrom.