Deadpool vs Thanos

In this 2015 Marvel miniseries, writer Tim Seeley and artists Elmo Bondoc and Tradd Moore pit the Merc with a Mouth against the Mad Titan in a cosmic clash of chaos and obsession. Spanning four issues, the story follows Deadpool and Thanos as their paths collide over a shared fixation, blending the series' signature dark humor with high-stakes intergalactic action. A standout odd-couple showdown, it showcases Marvel's ability to find fresh, entertaining friction between its most mismatched characters.