Medusa

Few characters can claim a Marvel pedigree as rich and enduring as Medusa, who burst onto the Silver Age scene in Journey into Mystery #116 in 1965, conjured by the legendary trio of Stan Lee, Jack Kirby, and Carl Hubbell. A cornerstone of the Inhumans mythos and a proud member of the Fantastic Four, she has spent six decades sharing pages with some of Marvel's most iconic figures — Black Bolt, Reed Richards, Ben Grimm, and the Human Torch among them. With 398 catalog appearances and a remarkable 20 recognized key issues to her name, she is far more than a supporting player; she's a genuine pillar of the Marvel Universe whose presence spans Fantastic Four, FF, and The Inhumans alike. If you're building a serious Silver Age collection or simply want to explore one of Marvel's most consistently compelling characters, Medusa is absolutely worth your time.